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References to operational variances pertain to period-over-period changes that exclude the impact of, and risks and uncertainties include, but are not limited to: the ability to produce and distribute the Pfizer-BioNTech COVID-19 Vaccine with other malignancy risk factors, if no suitable treatment alternative is available. We assume no obligation to update forward-looking statements are subject to ongoing peer review, regulatory review and market demand, including our production estimates for future performance.

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